Regenerative Medicine Current Lecture

Stem Cells and Type 1 Diabetes

The Spring 2025 Regenerative Medicine Lecture will be presented as a webinar on Thursday March 27th at 6 pm. Dr. Bryce Carey will be presenting this seminar.

Registration:

Registration is required to attend; following registration, you will receive a link to access the webinar. Register Here

Lecture Summary:

Type 1 diabetes (T1D) is a lifelong disease caused by the autoimmune destruction of insulin-producing islet cells (beta cells) in the pancreas. Insulin is a hormone that the body needs to process glucose, a key source of energy. Without insulin, no cell in the body can use or store glucose normally. Until the discovery of insulin just over 100 years ago, diagnosis of Type 1 diabetes (T1D) was a death sentence. Through discoveries in both engineering and molecular biology, modern technologies have improved how blood sugar is monitored and insulin delivered. Yet 100 years later the treatment paradigm remains unchanged. This talk will discuss the biology of Type 1 diabetes, current treatment options, and provide an overview of investigational therapies in clinical stage advancing stem cell-based approaches aimed at treating the underlying cause of T1D – the absence of insulin-producing cells.

Speaker Biography:

Dr. Bryce Carey received his BS in Cell Biology from UC Davis. He earned a PhD from MIT where he developed novel mouse models to study the mechanisms of somatic cell reprogramming during the generation of induced pluripotent stem cells (iPSCs). His post-doctoral work at Rockefeller University investigated how the intersection of metabolism and chromatin influences stem cell fate decisions. After joining Semma Therapeutics, which was acquired by Vertex Pharmaceuticals in 2019, he has led research efforts at Vertex Cell & Genetic Therapies (VCGT) to develop and improve protocols to generate stem cell-derived islets (SC-islets) for the treatment of Type 1 diabetes (T1D).

Presented by the College of Natural Sciences and Mathematics and the Center for Science and Math Success, the Regenerative Medicine Lectures are funded through a California Institute for Regenerative Medicine (CIRM) grant in collaboration with the UC Davis Stem Cell Program. This webinar is free and open to the public. 

For questions or more information about the Regenerative Medicine Lecture series, please contact Kimberly Mulligan at kimberly.mulligan@csus.edu.