Courses That I Teach

NSM21:  Freshman Seminar: Becoming an Educated Person 

BIO139: General Microbiology

BIO140: Medical Microbiology & Emerging Infectious Diseases

BIO134: Medical Mycology 

BIO144: Pathogenic Bacteriology

BIO15L: Laboratory Investigations in Biology

 

 

Research Projects/Interests

The Lindgren Laboratory incorporates the independent research projects of both Undergraduate and Masters-level Graduate students whose interests lie primarily in the fields of Pathogenic Bacteriology and Clinical Laboratory Sciences.  Our research has included a wide-spectrum of topics from characterization of antibiotic-resistant intestinal flora, development of molecular methods for identification of pathogens, ethnobotanical antibiotic identification, edible vaccines, Salmonella host-pathogen interactions, and studies on pathogenic E.coli.  Currently, the majority of our research is focused on Shiga toxin-producing E.coli (STEC).  We have been evaluating the prevalence of STEC in Northern California in ground beef, free-range grazing cattle, humans, and horses, and characterizing the numerous STEC isolates we have obtained from these sources. Bottom-line from our findings:  Cook your beef, Wash your hands, Get Vaccinated, use Antibiotics Judiciously, and CSUS students are awesome research scientists.

Masters Student Theses

2017   Isaac Shaker. Intron Mediated Enhancement of Gene Expression in C. elegans. 

2014   Benjamin Mooso. Cisplatin Resistance and ErbB3 in Bladder Cancer.

2013   Peter Yu. Survival of Uropathogenic Escherichia coli under Protozoan Predation

2013   Aaron Avila. Prevalence and characterization of integrons in multidrug-resistant non-clinical enteric bacterial isolates.

2010   Melissa Morris. Molecular Detection of fecal-bacterial contamination on grocery store shopping cart handles within the Sacramento region.

2009   Donica Larson. Prevalence of Shiga toxin-producing Escherichia coli in the Sacramento Valley Equine Population.

2009   Michelle Hopkins. Prevalence of Shiga toxin-producing Escherichia coli in Range-grazing Cattle.

2007   Margaret Werminski. Detection of Shiga toxin-producing Escherichia coli (STEC) in Clinical Stool Specimens by the Polymerase Chain Reaction (PCR).

2003   Philip Barruel. Isolation and Detection of Enterohemorrhagic E.coli from Retail Ground Beef.

2001   Priyatharshini Jeyabalasingam. Characterization of OmpR/EnvZ Regulated Genes in Salmonella    typhimurium.

2000   Julie Oliver. Enterohemorrhagic Escherichia coli Detected in Retail Ground Beef in the Sacramento Area Using Polymerase Chain Reaction.

1999  Pallavi Kumar. Identification and Characterization of Genes Regulated by the OmpR/EnvZ regulon in Salmonella typhimurium. 

Abstracts

*undergraduate student researcher   **masters student researcher

*Harvest, C., *J. Bowser, *I. Sturgill, *M. Blake, and S. Lindgren. 2016. Molecular Identification of Virulence factors in non-O157 Shiga toxin-producing E.coli from Free Range-Grazing Cattle in Northern California.  North.Calif. Am. Soc. Microbiol., Santa Clara, CA.

 *Arreola, Marcos, S. Lindgren. 2010. Antimicrobial Effects of the Common Manzanita. Abstr. SACNAS National Conference, Anaheim, CA.

 * Jones, G., S. Lindgren. 2010. The Effects of Oak Gall Juice on Bacteria.  SACNAS National Conference, Anaheim, CA.

 ** Larson, D. *A. Black, and S. Lindgren. 2010.  Prevalence of Shiga-toxin producing Escherichia coli in the Sacramento valley equine population.  Abstr. 110th Annu. Meet. Am. Soc. Microbiol, San Diego.

 **Werminski, M., and S. Lindgren. 2008. Detection of Shiga toxin-producing Escherichia coli (STEC) in clinical stool specimens by the polymerase chain reactions (PCR). Abstr. 48th Ann. Mtg. Intersci Conf. Antimicrob. Agnts & Chemo (ICAAC), 46th Ann. Mtg. Infect. Dis. Soc. Am.(IDSA).Washington, D.C.

 **Hopkins, M., **M. Werminski, **P. Barruel, **J. Oliver, and S. Lindgren. 2007. Prevalence and Characterization of Shiga-toxin Producing E.coli Strains in Retail Ground Beef, Culled Cattle, and Human Clinical Specimens in Northern California.   EMBO-FEMS-Leopoldina ECOLI 2007 Mtg: Facets of a versatile pathogen, Bad Staffelstein, Germany.

 *Williams, G.V., and S. Lindgren. 2005.  The Effect of Elderberry Juice on the Growth of Common Bacterial Organisms. Annual Biomedical Research Conference for Minority Students, Atlanta, GA. *National winner, Student Poster/Research Award.

 **Morris, M., and S. Lindgren.  2004.  Development of a Multiplex Polymerase Chain Reaction Assay to identify Enterohemorrhagic E.coli, Salmonella, Listeria monocytogenes, and Campylobacter pylori.  CSUPERB 16th Annual Biotechnology Symposium, San Jose, CA.

 Lindgren, S., R. Ballard, N. Ewing, D. Bell, L. Roberts, K. McReynolds, and M. McCarthy-Hintz. 2003.   Development of a Molecular Biology Interdisciplinary Group at CSU Sacramento. CSUPERB 15th Annual Biotechnology Symposium.

 **Barruel, P., and S. Lindgren. 2002. Development of an slt-specific Chemiluminescent Detection System for Identification of Enterohemorrhagic E. coli in Ground Beef.  Abstr. Spring Meet. North.Calif. Am. Soc. Microbiol., (NCASM) Santa Clara, CA. *First place winner student poster

 *Matthys, J., and S. Lindgren. 2002.  Viability of Low Levels of Enterohemorrhagic E. coli O157:H7 in Ground Meat When Stored at 4^oC.  Abstr. Spring Meet. North.Calif. Am. Soc. Microbiol., Santa Clara, CA.

 *Jobes, J. *T. Spaulding, *J. Freedle, and  S. W. Lindgren. 2001.  Viability of Enterohemorrhagic E.coli in consumable meat. Abstr. Spring Meet. North.Calif. Am. Soc. Microbiol., Oakland, CA. *First place winner, student poster award

 **Oliver, J., *C. Traylor, and S. Lindgren. 2000. Detection of Enterohemorrhagic E.coli in retail groundbeef in the Sacramento area. Abstr. 100th Annu. Meet. Am. Soc. Microbiol., and NCASM meeting.* First Place winner, student poster award at NCASM meeting.

 **Kumar,P., **P. Jeyabalasingam, *K. Fluegal, B. Ahmer, and S. Lindgren. 2000. Identification of OmpR/EnvZ regulated genes in Salmonella. Abstr. 100th Annu. Meet. Am. Soc. Microbiol.

Charkowski, A.O., S. Lindgren, R. E. Mandrell. 1999.  Investigation of Salmonella enterica - Alfalfa sprout interactions. Abstr. Annu. Meet., Am. Phytopathol. Soc. Quebec, Canada

 *Promenko-Lanier, M., **S. Ro, S. Lindgren, N. Ewing. 1999. Toward Edible HIV Vaccine. Abstr. International Cell Biology Approach to Microbial Pathogenesis Meeting, Portland, OR

 Stojiljkovic, I., *B. Wobbes, S. Lindgren, B. Ahmer, *N. Kruize, and F. Heffron. 1996. Salmonella typhimurium genes that undergo phenotypic switching.  Abstr. 96th Annu. Meet. Am. Soc.Microbiol.

Lindgren, S., I. Stojiljkovic, and F. Heffron.  1995. Isolation of Salmonella typhimurium mutants that lack a cytotoxic phenotype on macrophages.  Abstr. 95th Annu. Meet. Am. Soc. Microbiol.

Lindgren, S. W., J. E. Samuel, C. K. Schmitt, and A. D. O’Brien. 1992. Pathogenesis of Shiga-like toxin type II-related toxins in an orally infected murine model.  Abstr. 92nd Annu. Meet. Am. Soc. Microbiol.

Lindgren, S. W., A. D. O’Brien.  1992. Regulation of Shiga-like toxin type II and its role in virulence of enterohemorrhagic Escherichia coli in a murine model.   The 11th Ann. graduate research colloquium, USUHS, Bethesda, MD.

Schmitt, C.K., S. W. Lindgren, M. L. McKee, and A. D. O’Brien. 1991. Copy number and antigenic diversity of Shiga-like toxins in enterohemorrhagic Escherichia coli may affect pathogenesis.  Abstr. 91st Annu. Meet. Am. Soc. Microbiol.

Professional Associations

American Society for Microbiology 

Northern California Branch of the American Society for Microbiology