BIO 124 Syllabus
Clinical Hematology
Spring 2012
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Instructor Information
Objectives
Requirements
Technology
Schedule
Grades/Policies
Catalog Description
Basic principles and clinical laboratory procedures used in the study of blood; emphasis on morphological and chemical changes in the disease processes. Prerequisite: CHEM 161.
Instructors' Information
Instructors:
Rose Leigh Vines, Ph.D., MT(ASCP)
Professor Emeritus of Biological Sciences
E-mail: rlvines@csus.edu
Web page: http://www.csus.edu/indiv/v/vinesr
Office: SQU 126
Office Hours: By appointment
Jane Bruner, Ph.D., CLS, MT(ASCP)
Associate Dean of the College of Natural Sciences and Mathematics
E-mail: jbruner@csus.edu
Office: SQU 334
Office Hours: By appointment
Course Objectives
- describe the structure and function of the components of normal blood and bone marrow
- describe the pathological processes that occur in the blood and bone marrow
- describe the normal and abnormal events during hemostasis
- provide a background for students in Clinical Laboratory Technology and other allied health programs who are continuing their clinical training in professional and graduate programs
Required Textbook and Laboratory Materials
Required Textbook:Clinical Hematology and Fundamentals of Hemostasis, Denise Harmening, 5th Ed., F.A. Davis, 2009.
You can purchase the textbook through the Hornet Bookstore or online.
Required Laboratory Materials:
You will be required to provide and wear a
lab coat during both laboratories. Latex examination gloves and safety
goggles will be provided to you in the laboratory.
Technology Requirements
Students should be comfortable using a computer and willing to browse the Internet. This class requires online class participation in the Web assignments. In addition, RealPlayer software is required to view video streamed lectures and Adobe Acrobat Reader software is required for printing of class handouts. They can be downloaded free from the Internet.
All students need access to a high-speed (broadband) computer connection to the Internet (campus network or a DSL/cable modem) and a SacLink account. Sacramento State students can access the Internet from one of the campus student labs if a personal high-speed connection is not available. All students enrolled in BIO 124 must get a SacLink account by the first day of class.
Schedule
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Topics |
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Introduction to the
Course |
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Lecture: Introduction
to the Study of Blood |
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| Lecture:
Origin, Development and Anatomy of Blood and Blood-forming Organs Lab Intro: Staining Techniques |
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Lecture: Stem Cells,
Cytokinetics, and Erythropoiesis |
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Lecture: Hemoglobin
Structure, Synthesis, and Function |
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Lecture: Erythrocyte
Membrane Structure, Metabolism, and Destruction |
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| Lecture: Erythrocytosis
vs. Anemia Introduction to Case Studies |
2/13/12 |
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Lecture: Microcytic,
Hypochromic Anemias |
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Lecture: Megaloblastic
Anemias |
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Lecture: Hemolytic
Anemias - Intracorpuscular Disorders |
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Lecture: Hemolytic
Anemias - Hemoglobin Disorders |
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Lecture: Hemolytic
Anemias - Extracorpuscular Disorders |
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LABORATORY 1 |
March 3,4 or 10 |
| Lecture:
Aplastic Anemia and Pure Red Cell Aplasia RBC Case Study Presentations |
3/5/12 |
| RBC Case Study Presentations |
3/7/12 |
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RBC
Case Study Presentations |
3/12/12 |
| MIDTERM EXAMINATION -- RBC |
3/14/12 |
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SPRING BREAK |
3/19/12-3/25/12 |
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Lecture: Phagocyte
System - Granulocytes and Monocytes |
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Lecture: Immune System
(con't) |
3/28/12 |
| Lecture and Lab Intro: Hematopoiesis | 4/2/12 |
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Lecture: Non-Neoplastic
Leukocyte Disorders |
4/4/12 |
Lecture: Neoplastic
Leukocyte Disorders - Leukemia |
4/9/12 |
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Lecture: Leukemia
(con't) |
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Lecture: Leukemia
(con't) |
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WBC Case Study Presentations |
4/18/12 |
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LABORATORY 2 for all students in course |
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| Lecture: Myeloproliferative
Disorders; Lymphoma WBC Case Study Presentations |
4/23/12 |
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WBC Case Study Presentations |
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Lecture: Cytogenetics
and Molecular Diagnostic Techniques |
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MIDTERM EXAMINATION 2 -- WBC |
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Lecture: Hemostasis |
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Lecture: Hemostasis (con't) |
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EXAMINATION 3
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Exams, Grades and Grading Policies
There will be a total of 550 possible points in the course with three written exams (Exam 1 - 160 pts; Exam 2 - 120 pts; Exam 3 - 50 pts), two SacCT quizzes (each worth 20 pts), two laboratory quizzes (each worth 30 pts), a final morphology exam (80 pts), and two case study presentations (each worth 20 pts). The format for examinations will be different depending on the information covered on the exam. Examples of types of questions that may occur on some of the examinations include multiple-choice, matching, short answer, discussion, problem-solving, morphology identification, and case study interpretation. Content and format for student case study presentations will be discussed in class.
Attendance is required for all lectures and laboratories. Roll will be taken at all class meetings including for those students at a distance watching on video streaming. All students will attend laboratories on the Sacramento State campus. Absence from more than 2 lectures or either laboratory will result in a Final Grade of "WU" for the course. There are no make-up exams or laboratories given.
Final Grades are determined using the following criteria:
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A |
Outstanding achievement |
90% of 550 possible points |
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B |
Excellent performance; clearly exceeds course requirements |
80-89% |
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C |
Meets course requirements |
70-79% |
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D |
Passed, but not at average achievement standards |
60-69% |
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F |
Failure to meet class requirements |
less than 60% |
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Plus and minus grades may be given at the discretion of the Instructors. |
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Cheating
Policy
Anyone cheating in any capacity will be assigned a final grade of "F" for the course and a letter will be sent to the Student Conduct Officer in Student Affairs for inclusion in the student's file. No exceptions.
Laptop and Cell Phone Regulation
Laptop computers are to be used for note-taking only. All cell phones must be turned off or set on vibration mode while in class. No text messaging or e-mailing is permitted.
Add/Drop Policies
The add/drop policies for all on-campus and off-campus students in BIO 124 are the same as the Sacramento State add/drop policies. Students should refer to the Sacramento State Academic Calendar on the Web site (http://www.csus.edu/) for the appropriate add/drop dates.
Special Needs Accommodations
If you have special needs and require special accommodations, you need to provide documentation to SSWD, Lassen Hall 1008, 916-278-6955. Please discuss your accommodation needs with me after class or during my office hours early in the semester.